Human DPSCs

RRPFR0200

Human dental pulp stem cells (DPSC) are derived from dental pulp tissue obtained during routine dental procedures. These cells exhibit a similar phenotype and function to bone marrow-derived MSCs. They express CD 105, CD 90, and CD 70 markers, while exhibiting weakly expressed or negatively expressed markers of hematopoietic function such as CD 34, CD 45, CD 31, CD 14, and HLA-DR.DPSCs have the ability to develop induced pluripotent stem cells, which can differentiate into a variety of cell types, including odontogenic dentin cells, osteoblasts, chondrocytes, cardiomyocytes, neurons, adipocytes, corneal epithelial cells, melanoma cells, and insulin-secreting β-cells. In addition, DPSC exhibit high proliferative capacity and remain quiescent in the pulp, but respond rapidly to injury.

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Applications

In toxicology and drug screening, DPSC can be used as a reliable model for assessing drug toxicity and screening potential therapeutic compounds. In regenerative medicine, dentistry and cellular therapy, DPSC show promise in tissue regeneration and repair. In addition, DPSC has the potential to treat myotonic dystrophy by differentiating into muscle cells and replacing damaged tissue. For corneal replacement therapy, DPSCs can differentiate into corneal epithelial cells, providing a potential solution for corneal diseases. In the context of cardiovascular disease, DPSCs can be used to generate cardiomyocytes for cardiac regeneration.

Storage

Liquid nitrogen.

Shipping

Dry ice.

Product type

Human adult stem cells.

Growth mode

Adherent

Cell type

Stem cell

Growth conditions

37°C, 5% CO2.

Sources

Human dental pulp

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Human DPSCs

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