CD73 Proteins

RRPFR0192

CD73 is an enzyme that is encoded by the NT5E gene. AMP is frequently converted to adenosine by CD73. Purine 5-prime mononucleotides are converted to nucleosides at neutral pH by ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase), with AMP as the preferred substrate. Different forms of 5-prime nucleotidase can be identified from ecto-NT5 by their substrate affinities, need for divalent magnesium ions, ATP activation, and inorganic phosphate inhibition. These forms are found in the cytoplasm and lysosomes.

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Other Names

CD73, NT5E, 5-Nucleotidase, 5-NT, NT5, NTE.

Species

Human

Components

Lyophilized from 0.22 μm filtered solution in 20mM Tris,120mM NaCl,pH7.5 with trehalose as protectant.

Applications

WB, IHC-P, IF, FC assays.

Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Purity

> 90% as determined by SDS-PAGE.

Sources

Rat

* This product is for research only.

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