CD44 Proteins
RRPFR0188
CD44 is a type I transmembrane glycoprotein that binds to its ligands such as MMP, growth factors, cytokines, and hyaluronic acid, and subsequently triggers cell proliferation and survival signals by activating RTK through pathways such as Src/FAK, PI3K/AKT, and HGF/c-Met, inducing cell proliferation and survival.
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Other Names
CD44 Antigen, CDw44, Epican, Extracellular Matrix Receptor III, ECMR-III, GP90 Lymphocyte Homing/Adhesion Receptor, HUTCH-I, Heparan Sulfate Proteoglycan, Hermes Antigen, Hyaluronate Receptor, Phagocytic Glycoprotein 1, PGP-1, Phagocytic Glycoprotein I, PGP-I, CD44, LHR.
Species
Human
Applications
Cell marker.
Storage
Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Shipping
Room temperature.
Molecular Weight
38-50 kDa
Appearance
Lyophilized powder.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Tags
C-6*His
Sources
HEK293
* This product is for research only.
