CD105 Proteins

RRPFR0196

CD105 is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. CD105 contains an RGD tripeptide which is a key recognition structure in cellular adhesion, suggesting a critical role for endoglin in the binding of endothelial cells to integrins and/or other RGD receptors. CD105 is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. CD105 has been regarded as a powerful biomarker of neovascularization, and is associated with several solid tumor types.

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Other Names

END Protein, Human, HHT1 Protein, Human, ORW1 Protein, Human.

Species

Human

Applications

Hemangioblast markers, cancer drug targets.

Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Appearance

Liquid

Purity

> 95 % as determined by SDS-PAGE

* This product is for research only.

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